Myeloid cannabinoid CB1 receptor deletion confers atheroprotection in male mice by reducing macrophage proliferation in a sex-dependent manner

Yong Wang; Li Guo; Bingni Chen; George Shakir; Mario Volz; Emiel P. C. van der Vorst; Sanne L. Maas; Martina Geiger; Carolin Jethwa; Alexander Bartelt; Zhaolong Li; Justus Wettich; Nadja Sachs; Lars Mäegdefessel; Maliheh Nazari-Jahantigh; Michael Hristov; Michael Lacy; Beat Lutz; Christian Weber; Stephan Herzig; Raquel Guillamat‐Prats; Sabine Steffens

doi:10.1093/cvr/cvae125

Abstract

Although the cannabinoid CB1 receptor has been implicated in atherosclerosis, its cell-specific effects in this disease are not well understood. To address this, we generated a transgenic mouse model to study the role of myeloid CB1 signalling in atherosclerosis.

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Wang et al. (2024) studied this question.

synapsesocial.com/papers/68e65f99b6db6435875edd0e https://doi.org/10.1093/cvr/cvae125

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Myeloid cannabinoid CB1 receptor deletion confers atheroprotection in male mice by reducing macrophage proliferation in a sex-dependent manner

Abstract

Discussion

Cite This Study

Myeloid cannabinoid CB1 receptor deletion confers atheroprotection in male mice by reducing macrophage proliferation in a sex-dependent manner

Abstract

Discussion

Cite This Study

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