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June 5, 2024Cancer Immunology ResearchOpen Access

Pancreatic Epithelial IL17/IL17RA Signaling Drives B7-H4 Expression to Promote Tumorigenesis

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Authors

SCSusana Castro-PandoRHRian M. HowellLLLe Li

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Castro-Pando et al. (2024) studied this question.

synapsesocial.com/papers/68e65f99b6db6435875edd5chttps://doi.org/10.1158/2326-6066.cir-23-0527
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1WNT signaling in the tumor microenvironment promotes immunosuppression in murine pancreatic cancer2022 · 59 citations
  2. 2IL-17 can promote tumor growth through an IL-6–Stat3 signaling pathway2009 · 836 citations
  3. 3The Pancreatic Cancer Microbiome Promotes Oncogenesis by Induction of Innate and Adaptive Immune Suppression2018 · 1,408 citations
  4. 4Cellular heterogeneity during mouse pancreatic ductal adenocarcinoma progression at single-cell resolution2019 · 280 citations