Peculiarity of Insulin Resistance in Men with Type 2 Diabetes Mellitus and Overall, Gender Comparison of Associated Complications

Insulin is a polypeptide hormone composed of 51 amino acids and secreted by the β cells of the pancreatic islets of Langerhans.Insulin regulates and maintains healthy blood glucose levels within the body, overseeing the control of plasma glucose levels.In the process, it stimulates cells to utilize the available plasma glucose for the Adenosine triphosphate (ATP) synthesis and coordinates the conversion of glucose into glycogen that is stored away in the liver and partly in the muscle as fatty acids.On the other hand, insulin resistance is a condition where normal sensitivity of the cells to insulin is impaired and cannot respond to the stimulation of insulin.When the pancreas produces normal or even elevated amounts of insulin, the body's response to the insulin is poor.While the body can adjust normal functioning amounts of insulin and/or β cells being produced, insulin resistance can often result in a condition called diabetes mellitus, a group of diseases that affect the way the body regulates blood glucose levels.Diabetes mellitus is a condition characterized by chronic hyperglycemia.Hyperglycemia can be caused by many factors, one being insulin resistance.Though diabetes mellitus occurs in many forms and affects people of all genders and ethnicities, this article specifically discussed the peculiarity of insulin resistance in men with type 2 diabetes mellitus.Areas such as normal and abnormal forms of insulin secretion, insulin resistance syndrome, causes of the insulin resistance form of type 2 diabetes mellitus, its epidemiology, worldwide prevalence, and global burden, gender differences in insulin resistance, and management of insulin resistance type 2 diabetes mellitus were researched.The etiology of the complications associated with insulin resistance was also researched.