A Rare Complication of Hyperemesis Gravidarum-Wernickes Encephalopathy

Wernicke's encephalopathy is a rare neurological syndrome that presents in the setting of thiamine deficiency. It is mainly associated with excessive alcohol intake. other causes include malnutrition, malignancy, gastric bypass surgery hemodialysis and hyperemesis gravidarum. It is a very rare complication of pregnancy. Wernicke's encephalopathy is characterized by clinical triad which includes ataxia, acute delirium and oculomotor disturbances. MRI confirms the diagnosis by the presence of hyper signals most frequently in the periaqueductal level of thalami and mamillary bodies in these cases, we report three cases of wernicke's encephalopathy in the context of hyperemesis gravidarum that developed the classical clinical trial of wernicke's encephalopathy along with spontaneous nystagmus and typical imaging findings on the brain imaging. subsequent treatment with thiamine led to rapid improvement in the clinical status and favourable course of pregnancy.