Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
October 8, 2025BMC AnesthesiologyOpen Access

Remimazolam vs. dexmedetomidine for postoperative sedation in oral tumor patients undergoing free flap reconstruction: a randomized controlled pilot trial

View Full Paper
Ask AI
Bookmark
Share

Authors

YLYun LiuLWLi‐Kuan WangGXGuo‐Li Xiong

Discussion

Loading...

Member takes

Overview

Randomized controlled trial indicates remimazolam and dexmedetomidine have comparable efficacy, suggesting remimazolam may enhance hemodynamic stability.

Key Points

  • Emergence agitation incidence was similar between remimazolam and dexmedetomidine at 27.6% vs. 25.0%, p > 0.999.
  • Remimazolam notably reduced colloid use in the PACU, with 3.4% versus 32.1%, leading to a p-value of 0.005.
  • This randomized double-blind trial involved 60 patients undergoing microvascular reconstruction, with final analysis on 57 patients.
  • Findings underscore remimazolam's potential as a favorable option for postoperative sedation, given its rapid offset.

Cite This Study

Liu et al. (2025) studied this question.

synapsesocial.com/papers/68e6679587ecc93a24d1742ehttps://doi.org/10.1186/s12871-025-03346-x
View Full Paper
Ask AI
Bookmark
Share