October 8, 2025

A Review on Various Analytical Method Development and Validation for Simultaneous Estimation of Levo-Salbutamol and Ipratropium Bromide in Bulk and Pharmaceutical Dosage Form by RP-HPLC

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The developed RP-HPLC method allows simultaneous estimation of levosalbutamol and ipratropium bromide in dosage forms.
Using a mobile phase with potassium dihydrogen phosphate and ethanol, the separation was effective and achieved at pH 3.0.
Detection was performed with a UV detector at 245 nm, demonstrating the method's accuracy and precision.
The findings suggest that this approach could enhance routine quality control in pharmaceutical settings.

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This review presents an effective RP-HPLC method for quantifying levosalbutamol and ipratropium bromide, indicating its potential in quality control.

Sangeetha et al. (2025) studied this question.

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This review presents an effective RP-HPLC method for quantifying levosalbutamol and ipratropium bromide, indicating its potential in quality control.