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June 1, 2024Cell ReportsOpen Access

Wg/Wnt-signaling-induced nuclear translocation of β-catenin is attenuated by a β-catenin peptide through its interference with the IFT-A complex

Linh T. Vuong Marek Mlodzik

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Abstract

Wnt/Wingless (Wg) signaling is critical in development and disease, including cancer. Canonical Wnt signaling is mediated by β-catenin/Armadillo (Arm in Drosophila) transducing signals to the nucleus, with IFT-A/Kinesin 2 complexes promoting nuclear translocation of β-catenin/Arm. Here, we demonstrate that a conserved small N-terminal Arm

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Cite This Study

Vuong et al. (2024) studied this question.

synapsesocial.com/papers/68e66b2fb6db6435875f6ce2 https://doi.org/10.1016/j.celrep.2024.114362

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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