Genomic analysis reveals multiple SARS-CoV-2 recombinants in a patient coinfected with Delta and Omicron variants, highlighting pathways for viral evolution.
Viral recombination that occurs by exchanging genetic materials between two viral genomes coinfecting the same host cells is associated with the emergence of new viruses with different virulence. Herein, we detected a patient coinfected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta and Omicron variants and identified various recombinants in the SARS-CoV-2 full-length spike gene using long-read and Sanger sequencing.
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Sayama et al. (2024) studied this question.
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