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June 1, 2024JCO Precision Oncology

Keratin-Positive Giant Cell Tumor of Bone and Soft Tissue With HMGA2::NCOR2 Fusion in Children Under 10 With Response to Imatinib Therapy: A Case Series

Phassawan Rungsiprakarn Anne L. Ryan Daniel Wong Minjie Luo Ken Kazahaya Alexandre Arkader Loretta M. S. Lau Pamela Ajuyah Erin R. Rudzinski Portia A. Kreiger Derek Roebuck Lea F. Surrey Tiffany Foo

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Abstract

HMGA2::NCOR2 keratin-positive giant cell tumors in children with response to imatinib in an infant

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Rungsiprakarn et al. (2024) studied this question.

synapsesocial.com/papers/68e66c53b6db6435875f7464 https://doi.org/10.1200/po.23.00659

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Keratin-Positive Giant Cell-Rich Tumor in Early Infancy: Metastatic Presentation and Imatinib ResponseOriginal Research · 2026
2Acral Mesenchymal Spindle Cell Neoplasm With a Novel HMGA2::NCOA2 FusionOriginal Research · 2025
3HGG-10. YAP1-MAML2 FUSION IN YOUNG CHILDREN WITH PEDIATRIC HIGH-GRADE GLIOMA: A CASE REPORT2024 · 1 citations
4Giant Cell Tumor of Bone in Patients under 16 Years Old: A Single-Institution Case SeriesCase Report · 2021 · 18 citations
5A Rapidly Growing Cervical Tumor in an Infant: Sarcoma with <i>BCOR</i> Gene Alterations.Original Research · 2026

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Aggressive infantile melanoma arising in a congenital nevus with rare <i>BRAF</i> and <i>BCOR</i> mutations: a case report and literature review of pediatric melanoma2026

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