Drug Induced Gingival Overgrowth: A Case Study and Clinical Analysis

Gingival enlargement is the most common side effect seen with the use of three major classes of drugs namely anticonvulsants, calcium channel blockers and immunosuppressants.We reported a case of 42-year-old female treated with Amlodipine for 3 years and developed gingival overgrowth in past 1 year.The GE had affected both mandibular and maxillary arches.Amlodipine was suspected for the GE in agreement with her physician.One month after the substitution of drug with the physician's consent and periodontal therapy, the GE was subsided completely.Later, the deep periodontal pocket measuring ≥5mm were treated with surgical periodontal therapy and patient was followed up regularly for 3 months.No recurrence of gingival enlargement was experienced by the patient for next 1 year.This unique case should encourage every dental practitioner to be diligent while treating such cases and to consider the potential side effects of using these drugs.