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June 1, 2024Journal of Clinical Oncology

Real-world outcomes (RWO) with tandem transplantation in patients (pts) with newly diagnosed multiple myeloma (NDMM).

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Authors

HPHarsh ParmarABAnna BarcellosNBNoa Biran

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Overview

Retrospective observational study demonstrates improved survival with tandem transplantation in newly diagnosed multiple myeloma, highlighting underutilized clinical benefits.

Key Points

  • Overall survival improves significantly with tandem transplantation in newly diagnosed multiple myeloma, extending the duration before initiating subsequent therapy.
  • Median overall survival was not reached versus 108.1 months for single stem cell transplant, corresponding to an overall survival hazard ratio of 0.47.
  • Retrospective, observational study analysis using a propensity score model evaluates clinical records, supporting broader tandem transplantation adoption.

Cite This Study

Parmar et al. (2024) studied this question.

synapsesocial.com/papers/68e67069b6db6435875fb23fhttps://doi.org/10.1200/jco.2024.42.16_suppl.7564
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effect of maintenance therapy (MT) on real-world outcomes (RWO) of patients (pts) with newly diagnosed multiple myeloma (NDMM) post stem cell transplant (SCT).2024 · 2 citations
  2. 2Comparison of tandem and single autologous stem cell transplantation in multiple myeloma: a retrospective propensity score-matching study2024
  3. 3Comparative analysis of single versus tandem autologous stem cell transplantation in patients with multiple myeloma in Korea: the KMM2102 study2024 · 1 citations
  4. 4P54 | EVOLVING OUTCOMES IN MULTIPLE MYELOMA REAL-WORLD PRACTICE: 30-YEARS SINGLE CENTER EXPERIENCE2026
  5. 5Impact of second autologous stem‐cell transplantation at relapsed multiple myeloma: A French multicentric real‐life study2024 · 4 citations