Ab0662 the Ultrasound 7 Score in the Assessment of Synovitis in Rheumatoid Arthritis Correlation With Clinical Disease Activity Indices in Daily in Latin America Daily Rheumatologic Practice

Background: Grey-scale and power Doppler ultrasonography are extensively used to detect synovial inflammation and appreciate disease activity, in addition to clinical and laboratory data, in order to apply the proper therapeutic measures, monitor the patients and assess the outcome [1]. Objectives: The aim of the paper was to assess value of ultrasound 7 score (US7) in the detection of synovitis in rheumatoid arthritis (RA) and its correlation with clinical disease activity indices CDAI. Methods: A total of 120 patients with suspicion or diagnosis of RA were included. Disease activity was assessed by clinical disease activity indices CDAI. Erythrocyte sedimentation rate was measured, and simple erosion narrowing score was used for radiography scoring. Musculoskeletal US7 score was done which combines each joint score for synovial proliferation (gray-scale ultrasound GSUS7) and vascularization (power Doppler ultrasound PDUS7). Results: Detailed joint region examination by US7 score was done. Dorsomedian aspect of wrist (92%), dorsal aspect of metacarpophalangeal joint (MCP) II (96%), and dorsal aspect of phalangeal interproximal (PIP) II and III (92%), dorsal aspect of metatarsophalangeal (MTF)II (99%) and V (89%) were the most affected joint regions with synovitis by GSUS. However, for detection of synovitis by PDUS, dorsomedian aspect of wrist and dorsal aspect of MCP, PIP II, and PIP III were involved (45%). Erosions were found most in radial aspect of MCP II (70%), lateral aspect of metatarsophalangeal joint V (72%), and dorsal aspect of PIP II (64%) and PIP III (43%). All clinical disease activity indices CDAI were correlated with GSUS7 and PDUS7 synovitis. Our results show a positive, moderate inter-relation, for both GSUS (p=0.67, statistically significant, p=0.009), and PDUS score (r= 0.5279, p= 0.0006), Conclusion: US7 was simple and practical sum scoring system for use in the detection of synovitis in patients with RA. The correlations between the clinical disease activity indices, erythrocyte sedimentation rate, duration of illness, radiographic score, and components of the US7 score reflects the value of US7 score in assessment of disease activity and severity. REFERENCES: [1] Backhaus M, Ohrndorf S, Kellner H, et al. Evaluation of a novel 7-joint ultrasound score in daily rheumatologic practice: a pilot project. Arthritis Rheum. 2009;61(9):1194–1201. Acknowledgements: SOCIEDAD PERUANA DE REUMATOLOGIA. Disclosure of Interests: None declared.