We have been investigating magnetic drug delivery systems (MDDS), which can selectively deliver drugs to affected areas within the body using a magnetic field. In this study, we developed Magnetic Pickering Emulsions (MPEs) as a novel drug delivery carrier. MPEs can not only induce and accumulate drugs at the targeted site but also control the drug release rate using a magnetic field. In this study, we prepared MPEs using ferromagnetic magnetite nanoparticles and evaluated the control of drug release rate by the magnetic force. MPEs with a particle diameter of several tens of μm gradually released the encapsulated substance for 60 minutes under an applied magnetic field of less than 3 T. On the other hand, for 30 minutes under a magnetic field of more than 4 T, the release rate increased about 2.6 times faster than that under 3 T. These results indicate that MPEs can control the drug release rate by magnetic force.
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Odani et al. (2024) studied this question.
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