The Role of Clostridium Difficile in the Development of Antibiotic-Associated Diarrhea in Early-Aged Children

Interest in studying the problem of diarrhea in children is due to their wide distribution (1-1.2 billion cases per year worldwide according to WHO, 2010), polyetiology, difficulty of differential diagnosis and tendency to acute and chronic course. In recent years, foreign and domestic authors have attached increasing importance to the so-called antibiotic-associated diarrhea (AAD), components: 6-40% in the structure of intestinal diseases. In the etiological structure of AAD in young children, the share of C.difficile infection was 47%. A rusk factor for development is also combination therapy with antibiotics.