Relationship between blood lipid panel with body mass, smoke exposure, dyspnea, physical activity, and quality of life in patients with dyslipidemia

Introduction Dyslipidemia defined as decreasing or rising the concentration of lipid molecules in blood serum. Dyslipidemia-related cardiovascular structure changes are accepted as an important public health problem throughout the world. Medical treatment, changes in diet and physical activity or structured exercise programs should be applied together in the treatment of dyslipidemia. Our aim was to assess relationships between blood lipids and body mass, smoke exposure, dyspnea perception, physical activity and quality of life in patients with dyslipidemia. Methods Forty-one participants were enrolled in this study (25F/16M, mean age:43.12±12.39 years, mean body mass index:28.17±5.34 kg/m2). Dyspnea perception assessed with mMRC dyspnea scale, physical activity level assessed with International Physical Activity Questionnaire – Short Form (IPAQ), and quality of life assessed with Short Form-36 Quality of Life Questionnaire (SF-36). Results Serum LDL amount has positive relationship with vitality score (r:0.305; p:0.047) and role limitations due to emotional problems score of SF-36 (r:0.325; p:0.048), and negative relationship with physical activity category of IPAQ (r:-0.305; p:0.045). Serum HDL amount has negative relationships with smoke exposure (r:-0.356; p:0.024). Serum total cholesterol amount has negative relationship with walking score (r:-0.422; p:0.007), total score (r:-0.404; p:0.01) and physical activity category (r:-0.405; p:0.01) of IPAQ. Serum triglyceride amount has positive relationship with body mass index (r:0.371; p:0.02). And also body mass index has positive relationship with serum triglyceride amount (r:0.371; p:0.02), mMRC score (r:0.642; p:0.024), and negative relationship with serum HDL amount (r:-0.286; p:0.038), physical function score (r:-0.487; p:0.004), role limitations due to physical problems score (r:-0.414; p:0.017) of SF-36, and walking score of IPAQ (r:-0.305; p:0.046). Smoke exposure has negative relationship with social function score of SF-36 (r:-0.355; p:0.039). Daily sitting time of IPAQ has positive relationship with mMRC score (r:0.658; p:0.02). Moderate intensity physical activity score of IPAQ has positive relationship with social function score of SF-36 (r:0.512; p:0.002). Walking score of IPAQ has positive relationship with role limitations due to emotional problems score of SF-36 (r:0.408; p:0.017). Conclusions According to our results, decreased physical activity (including vigorous, moderate intensity or walking activities) may cause an increase in blood lipids, except HDL; body mass index, and a decrease in quality of life. Additionally increased blood lipids decrease different areas of quality of life. Increased body mass and age may cause rising in blood lipids, and a decrease in physical activity and quality of life. Our results showed that increasing physical activity may decrease blood lipids, body mass index, dyspnea perception, and increase quality of life patients with dyslipidemia.