Cavitating Lung Lesions in Adults with Crohn’s Disease

Different pulmonary changes occur in some patients with Crohn's disease.This study explored literature reports of necrobiotic pulmonary nodules that may present clinically with shortness of breath and dyspnea, or alternatively, be completely asymptomatic and simply detected by radiographic studies.These may be reflective of an extra-intestinal manifestation of Crohn's disease, similar to focal lesions in bone, skin or other urogenital site with accompanying granulomatous inflammation.Frequency of this pulmonary entity may be much higher than clinically appreciated, in part, owing to prior limitations in physician recognition and their reported complete responsiveness to courses of treatment with corticosteroids.