Evalution the association between the infection with Cryptosporidum spp. and some immunological parameters

The coccidian infection cryptosporidiosis affects humans, domestic animals, and untamed vertebrates. Cryptosporidium organisms induce disorders of the digestive and respiratory systems in farm animals, resulting in poor animal health and significant economic losses. The primary objective of this research was to assess the prevalence of Cryptosporidium spp. among diverse groups of individuals residing in Al-Anbar Province. These individuals sought medical care across a range of healthcare facilities, this encompasses facilities such as Al-Ramadi Maternity and Children's Hospital, Fallujah Teaching Hospital, IDP camps, well-frequented health centers in Al-Anbar Province, and privately-operated laboratories. The data collection period encompassed the timeframe from March 2022 to February 2023. Additionally, the study aimed to investigate potential correlations between Cryptosporidium spp. infection and various factors, including age, gender, place of residence, and seasonal variations, as well as evalute the immunological parameters as IgM ,IgG ,IL-4 and IL-18. A total of 420 stool samples and blood serum samples were collected from individuals, including both children and adults, as well as males and females, across Al-Anbar province and private laboratories. This comprehensive study spanned from March 2022 to February 2023. Among the individuals tested, 60 were found to be infected with Cryptosporidium spp., resulting in an infection rate of 14.3%. In contrast, 360 individuals tested negative for Cryptosporidium spp., accounting for an 85.7% non-infection rate based on microscopic examination. The research included 28 (46.7%) participants who were male and 32 (53.3%) who were female. No statistically significant variances were noted between Cryptosporidium spp. infection and gender.