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June 1, 2024

[The Application Study of Voriconazole and Its Metabolites Concentration Monitoring in Allogeneic Hematopoietic Stem Cell Transplantation Patients].

Hong-Chun Wang Lei Wang Meng Li Lei Shi Huihui Sun Hongxing Liu Hongling Ou

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Abstract

To explore the application value of simultaneous monitoring of voriconazole (VRCZ) and voriconazole N-oxide (VNO) in efficacy and safety of VRCZ in the prevention and treatment of fungal infections in allogeneic hematopoietic stem cell transplantation (allo-HSCT) patients before engraftment (i.e., days +1 to +30 after transplantation).

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Wang et al. (2024) studied this question.

synapsesocial.com/papers/68e672e6b6db6435875fdbec https://doi.org/10.19746/j.cnki.issn.1009-2137.2024.03.045

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Voriconazole as a Secondary Prophylaxis for Invasive Fungal Infections in Allogeneic Hematopoietic Stem Cell Transplantation: Real-world Evidence From a Major Transplantation Center in TaiwanCohort Study · 2026
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5Pharmacogenomic Profiling of Voriconazole Enables Predicting Its Toxicity in Pediatric Leukemia and Hematopoietic Stem Cell Transplant Recipients—A Prospective Study From North IndiaCohort Study · 2026