Antimicrobial activity of some vinyl-triazole derivatives

Mycoses and bacterioses in agricultural crops are very devastating, bringing enormous economic damage through direct crop losses and compromising it due to pathogen toxin pollution, which makes them toxic to humans and animals. Chemical plant protection procedures often become ineffective due to the easy adaptation of causative agents to pesticides, the reduction of the protective effect under the influence of unfavorable conditions, toxicity, ecological consequences. Starting from this, the aim of the research consisted in the identification of new compounds with antifungal (Fusarium avenaceum) and antibacterial (Erwinia amilovora, E. carotovora, Xanthomonas campestris) activity in in vitro conditions for further utilization in plant protection measures. Based on the growth of fungal colonies and minimum bactericidal concentration, it was found that vinyl-triazole derivatives EPS-869, EPS-877, EPS-880, EPS-892, EPS-165 (0,00125; 0,0025; 0,005; 0, 01%) shows high antimicrobial activity, the phenomenon being due in particular to the compound factor.