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May 31, 2024Journal of the American Heart AssociationOpen Access

Associations Between Genetically Predicted Iron Status and Cardiovascular Disease Risk: A Mendelian Randomization Study

Alexa Barad Andrew G. Clark Eva K. Pressman Kimberly O’Brien

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Abstract

Mendelian randomization (MR) studies suggest a causal effect of iron status on cardiovascular disease (CVD) risk, but it is unknown if these associations are confounded by pleiotropic effects of the instrumental variables on CVD risk factors. We aimed to investigate the effect of iron status on CVD risk controlling for CVD risk factors.

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Barad et al. (2024) studied this question.

synapsesocial.com/papers/68e67624b6db643587600470 https://doi.org/10.1161/jaha.124.034991

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