May 31, 2024CureusOpen Access

Severe Hypertrophic Cardiomyopathy Associated With Hydroxychloroquine in a Young Woman With Systemic Lupus Erythematosus: A Case Report and Review of the Literature

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Authors

BBBernard J. Treves BrownUniversity of Manchester CJChristy JosephMontefiore Medical Center VTVarsha TalankiSUNY Downstate Health Sciences University

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Implication

Case report demonstrates severe hypertrophic cardiomyopathy in a young woman with systemic lupus erythematosus, highlighting rare cardiotoxic effects of hydroxychloroquine therapy.

Key Points

Severe hypertrophic cardiomyopathy can develop during hydroxychloroquine therapy, presenting alongside embolic stroke in systemic lupus erythematosus.
Transthoracic echocardiogram evaluation confirmed profound ventricular wall thickening in a 23-year-old woman with suspected Libman-Sacks endocarditis.
Highlights rare cardiac adverse effects linked to disrupted lysosomal degradation, warranting vigilant cardiovascular surveillance beyond retinopathy.

Cite This Study

Brown et al. (2024) studied this question.

synapsesocial.com/papers/68e6774bb6db643587600f09 https://doi.org/10.7759/cureus.61452

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Implication

Case report demonstrates severe hypertrophic cardiomyopathy in a young woman with systemic lupus erythematosus, highlighting rare cardiotoxic effects of hydroxychloroquine therapy.

Severe Hypertrophic Cardiomyopathy Associated With Hydroxychloroquine in a Young Woman With Systemic Lupus Erythematosus: A Case Report and Review of the Literature

Discussion

Member takes

Implication

Key Points

Cite This Study

Severe Hypertrophic Cardiomyopathy Associated With Hydroxychloroquine in a Young Woman With Systemic Lupus Erythematosus: A Case Report and Review of the Literature

Discussion

Member takes

Implication

Key Points

Cite This Study

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