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May 31, 2024PeerJOpen Access

Effect of GnRH agonist down-regulation combined with hormone replacement treatment on reproductive outcomes of frozen blastocyst transfer cycles in women of different ages

Jianghuan Xie Jieqiang Lu Huina Zhang

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Abstract

To investigate the effect of GnRH agonist (GnRH-a) down-regulation prior to hormone replacement treatment (HRT) to prepare the endometrium in frozen embryo transfer (FET) cycles in women of different ages.

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Cite This Study

Xie et al. (2024) studied this question.

synapsesocial.com/papers/68e67752b6db64358760140c https://doi.org/10.7717/peerj.17447

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1The effect of gonadotropin-releasing hormone agonist downregulation in conjunction with hormone replacement therapy on endometrial preparation in patients for frozen–thawed embryo transfer2024 · 5 citations
2GnRH agonist pretreatment in hormonal endometrial preparation: a comparison of two protocols for frozen embryo transfer outcomes2025 · 1 citations
3Early GnRH-agonist therapy does not negatively impact the endometrial repair process or live birth rate2024 · 1 citations
4Clinical Outcomes in Hormone Replacement Therapy (HRT)-Frozen Embryo Transfer (FET) Protocol Increased by Administering Gonadotropin-Releasing Hormone Agonist (GnRH) in the Initial Stage of the Luteal Phase: A Retrospective Analysis2024 · 2 citations
5Impact of GnRH Agonist Pretreatment on Frozen-Thawed Embryo Transfer Outcomes of Overweight/Obese Women Undergoing Hormone Replacement Therapy.2025