Multicentre case series reports acute kidney injury during acyclovir therapy in varicella-zoster virus central nervous system infections, highlighting renal safety.
Background Systematic treatment with intravenous acyclovir is usually given when varicella zoster virus (VZV) DNA is isolated in cerebrospinal fluid (CSF), indicating central nervous system (CNS) involvement. Our study aimed to describe therapeutic management and acute kidney injury (AKI) occurrence during acyclovir treatment of VZV infection with CNS involvement.
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Contamine et al. (2024) studied this question.
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