Frequency and association of H pylori with severity of Gastritis according to age and gender: A Retrospective Study conducted at a Tertiary Care Hospital in Karachi, Pakistan.

Objective: To observe the frequency of H. pylori in relation to the type, severity, and anatomical site of gastritis according to age and gender. Study Design: Retrospective study. Setting: Endoscopy Suite of Medical Unit-III, Ward 7, Jinnah Postgraduate Medical Center, Karachi. Period: 2nd January 2019 to 5th January 2022. Methods: On the patients, aged more than 12 years, who underwent upper GI endoscopy the data was analyzed using the Statistical Package for the Social Sciences version 25 using significant p-value of < 0.01. Results: 243 patients were included in the study. Among them 100(41.2%) had H pylori positive gastritis. Out of the total, 47% were between the ages of 26 and 40, 41% reported complaints of epigastric pain; 27% had Grade B esophagitis; 50% exhibited mild severity of gastritis and 57% had pan gastritis pertaining to the anatomical site of the gastritis. However, it's crucial to note that all these findings were statistically insignificant except its correlation with severity of gastritis, which was significant. Conclusion: H. pylori-associated gastritis was equally common in both genders in younger age group. There was a statistically significant link between H. pylori infection and severity of gastritis (P-value< 0.01). Thus, the burden of gastritis can be reduced with H Pylori’s early detection and treatment.