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The state of equilibrium of Dosha, Dhatus, Malas is health and its disequilibrium is known as disease. This disequilibrium may either be Vriddhi or Kshaya. Asthiis thefifth Dhatu among the seven Dhatus .It is the seat of vatadosha and carrying the function of dehadharana. Asthikshayais one of the condition described by Acharya Charak under 18 types Kshaya in which there is kshayaof Asthi Dhatu. According to the principle of Ashraya-ashrayee Bhava, Asthi & Vata are inversely proportional to each other regarding Vriddhi and Kshaya. Vriddhvata leads to Kshaya of Asthi Dhatu.The symptoms of Asthikshaya resemble to Osteoporosis which is major health problem of ageing population. It is a skeletal disease characterized by low bone mass and micro architectural deterioration of bone tissue, with a consequent increase in bone fragility and susceptibility to fracture.
- et al. (Thu,) studied this question.