HIV and Undetectable = Untransmittable (U=U)

Advances in development of antiretroviral therapy and increased utilization of pre-exposure prophylaxis agents have effectively decreased the incidence of HIV sexual transmission. Conversely, at the same moment, there is an epidemic of other sexually transmitted infections in similar high-risk populations that is increasing at an alarming rate. This review aims to provide a summary of the origins and benefits of the Undetectable = Untransmittable (U=U) HIV campaign and the positive impact it has had on HIV prevention, while addressing the concomitant need for implementation of effective strategies to prevent further rise in sexually transmitted infections.