Gold-Catalyzed Cascade Reaction of Yne-Enones with Iminooxindoles, Access to 3,2′-Pyrrolidinyl-Spirooxindole Derivatives

Herein, a gold-catalyzed cascade reaction of yne-enones with iminooxindoles has been developed through a cascade cycloisomerization/(3 + 2) annulation process. This approach provides a straightforward and efficient route for the synthesis of functionalized 3,2'-pyrrolidinyl-spirooxindoles in high reactivity and broad substrate scope with excellent