Answers are grounded in this paper and cite their sources.
Thyroid hormones have systemic effects on the human body and play a key role in the development and function of virtually all tissues. They are regulated via the hypothalamic-pituitary-thyroid (HPT) axis and have a heritable component. Using genetic information, we applied tissue-specific transcriptome-wide association studies (TWAS) and plasma proteome-wide association studies (PWAS) to elucidate gene products related to thyrotropin (TSH) and free thyroxine (FT4) levels.
No takes yet. Share an insight, caveat, or question.
Monteiro-Martins et al. (2024) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: