Reproducibility study to simulate a chain of collapsible contracting lymphangions with progressive valve closure

This paper presents a reproduced computational model of lymphatic collecting vessels. The model was originally introduced by {bertram2011simulation}, and comprises a series of contractile segments, known as lymphangions, interconnected by secondary lymphatic valves. The model focused on elucidating the pumping behavior of contracting lymphangions and deriving pump-characteristic curves, by incorporating pressure-dependent valve resistance, passive elasticity, and active contraction terms in multiple lymphangions connected in series. The original model was implemented and solved using MATLAB software. In our work, we reproduce {bertram2011simulation}'s original model within the CellML framework, and present the results.