44 Impact of the danish comorbidity index for acute myocardial infarction score on 30-day unplanned readmission rates and causes in hospitalised patients with acute coronary syndrome

Introduction This study aimed to investigate the association of the DANish CoMorbidity Index for Acute Myocardial Infarction (DANCAMI) score with the 30-day unplanned readmission rates and causes and in acute coronary syndrome (ACS) patients. Methods Between October 2015 to December 2019, index hospitalisations with a principal diagnosis of ACS were extracted from the National Readmission Database and stratified by their DANCAMI score using International Classification of Diseases – 10th edition codes. Thirty day unplanned readmission rates and causes were analysed, and the factors associated with readmission were assessed. Results from multivariable regression were reported as adjusted odds ratios (aOR) with 95% confidence intervals (95% CI). Results There were 2,066,328 ACS admissions in the study period. Of which 173,304 (8.4%) had a DANCAMI score of 0, 602,640 (29.2%) had a DANCAMI score of 1–3, 327,046 (15.8%) had a DANCAMI score of 4–5 and 963,338 (46.6%) had a DANCAMI score ≥6. There were 189,240 (9.2%) unplanned readmissions within 30 days. Patients with a DANCAMI score of ≥6 were more likely to be older, comorbid and have an index presentation of non-ST-elevation ACS compared to their lower DANCAMI score counterparts. A DANCAMI score ≥6 (aOR 1.30 95% CI 1.27–1.34), age (aOR 1.01 95% CI 1.01–1.01), female sex (aOR 1.09 95% CI 1.08–1.10) and index ST-elevation ACS (aOR 1.03 95% CI 1.01–1.04) were associated with readmission (all p<0.001). Conclusion Increased comorbidity burden using the DANCAMI score was independently associated with higher overall readmissions in patients with ACS. Conflict of Interest None