Metabolic analysis reveals modest and transient functional changes in the infant gut microbiome following gestational diabetes, indicating limited long-term developmental disruption.
Gestational diabetes mellitus (GDM) is a metabolic complication that manifests as hyperglycemia during the later stages of pregnancy. In high resource settings, careful management of GDM limits risk to the pregnancy, and hyperglycemia typically resolves after birth. At the same time, previous studies have revealed that the gut microbiome of infants born to mothers who experienced GDM exhibit reduced diversity and reduction in the abundance of several key taxa, including
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Chieu et al. (2024) studied this question.
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