What type of study is this?

This is a Cohort Study study (also classified as: In Vitro Study).

October 8, 2025Scientific ReportsOpen Access

The role of vitamin C in melanoma cell death via activation of cytochrome C and TNF-α protein expression

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This study demonstrates enhanced apoptosis in melanoma cells, highlighting vitamin C's role in cytochrome c and TNF-α expression.

Vitamin C significantly increases cytochrome c and TNF-α expression in melanoma cells, inducing apoptosis.
Caspase-3 expression showed meaningful increments at vitamin C concentrations of 3,000 µM and 5,000 µM.
Exposure for 12 hours resulted in observable signs of cell death, indicating the effectiveness of vitamin C treatment.
Gene expression analysis revealed that vitamin C initiates multiple apoptotic pathways in B16-F10 melanoma cells.

Sutedja et al. (2025) studied this question.

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October 8, 2025Scientific ReportsOpen Access

View Full Paper

Ask AI

Bookmark

Authors

This study demonstrates enhanced apoptosis in melanoma cells, highlighting vitamin C's role in cytochrome c and TNF-α expression.

Vitamin C significantly increases cytochrome c and TNF-α expression in melanoma cells, inducing apoptosis.
Caspase-3 expression showed meaningful increments at vitamin C concentrations of 3,000 µM and 5,000 µM.
Exposure for 12 hours resulted in observable signs of cell death, indicating the effectiveness of vitamin C treatment.
Gene expression analysis revealed that vitamin C initiates multiple apoptotic pathways in B16-F10 melanoma cells.

Sutedja et al. (2025) studied this question.

View Full Paper

Ask AI

Bookmark