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May 25, 2024Human Molecular Genetics

Elucidating the impact of Y chromosome microdeletions and altered gene expression on male fertility in assisted reproduction

Nasrin Pazoki Mitra Salehi Seyed Abdolhamid Angaji Meghdad Abdollahpour‐Alitappeh

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Abstract

Genetic abnormalities like Y chromosome microdeletions are implicated in male infertility. This study investigated the association of azoospermia factor (AZF) region microdeletions with unsuccessful assisted reproductive techniques (ART), including in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI).

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Cite This Study

Pazoki et al. (2024) studied this question.

synapsesocial.com/papers/68e686d2b6db64358760fc95 https://doi.org/10.1093/hmg/ddae086

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Y chromosome and male fertility: The AZF genes and their deletionReview · 2026 · 1 citations
2Evaluation of Hormonal Profile and Y Chromosome Microdeletion in Azoospermic and Severely Oligozoospermic Males Presenting with Primary Infertility2025
3Infertility Challenge in a Cryptozoospermic Patient With Y Chromosome Microdeletion2024
4Hormonal Profiles and Y Chromosome AZF Microdeletions in Moroccan Azoospermic Men: A Molecular and Endocrine StudyOriginal Research · 2026
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