A stagerring recovery of an adolescent boy with crescentic glomerulonephritis despite numerous poor prognostic factors following early therapy

Poststreptococcal glomerulonephritis (PSGN) is a frequent, generally benign nephritis of childhood, yet, rarely shows a more aggressive rapidly progressive pattern as crescentic glomerulonephritis (CGN) histologically. It might end up in irreversible kidney failure, unless diagnosed and started a specific therapy shortly. However, due to the shortage of data for children, adult guidelines for CGN, have still made up the cornerstone of the therapy and management strategies in childhood. There are numerous parameters ending up with a poor outcome; alike elderly child age, male gender, initial severe acute kidney injury, nephrotic syndrome, hypertension and widespread crescents in 100% of glomeruli. This case presented here, reports a unique clinical and histological recovery story of a 13-year-old boy with poststreptococcal glomerulonephritis associated rapidly progressive glomerulonephritis (PSGN) following a promptly provided aggressive therapy, despite associated serious poor prognostic factors.