Challenges for Follow-Up of Sides Effects and Sequelae After Ovarian and Endometrial Cancers Treatments

Purpose : Multimodal treatments for ovarian cancer (OC) and endometrial cancer (EC) are susceptible to induce long-term disorders and to alter the quality of life of patients. This review aims to underlines the necessity to move forward to better identify and manage the sides effects and sequelae in order to enhance quality of life of gynecological cancer survivors. Methods : narrative review. Results : OC and EC patients experience a wide range of symptoms that may persist over time: fatigue, pain, nausea, abdominal discomfort, peripheral neuropathy, anxiety, depression , sleep disorders, menopausal symptoms and sexual disorders. Management of these disorders need to be included in follow-up care plans that help to summarize cancer history, long-term side effects and to give information on health promotion and prevention. Long term patient-reported outcome measures may contribute to cover the full range of these toxicities such as fatigue, lymphedema, and cognitive impairment. The coordination between the supportive care and the health-care provider is crucial needed to offer a personalized management for OC and EC survivors and to ensure adapted supportive care along survivorship. Conclusion: Gynecological cancer survivors have specific needs that should be addressed systematically by caregivers. The implementation of a survivorship care plan after cancer treatment is recommended and can be useful to monitor patient's needs. Coordination and development of networks of supportive care providers for long-term survivors after gynecological cancer is needed to reduce long-term toxicities and improve the quality of life of these patients.