Site-Selective Silylation of Carbohydrates by Molecular Catalysts

Site-selective functionalization of saccharides has been actively studied in recent years because it offers the possibility of simplifying synthetic schemes of sugar-related compounds by reducing the steps for protection and deprotection. Since molecular catalysts were able to promote various functional group transformations that cannot be catalyzed by enzymes, a variety of catalytic reaction systems using molecular catalysts have been developed. In this minireview, some examples of site-selective silylation of sugar derivatives were described briefly.