A Randomized, Double-Blind, Placebo-Controlled Clinical Trial on the Effect of a Dietary Supplement Containing Dry Artichoke and Bergamot Extracts on Metabolic and Vascular Risk Factors in Individuals with Suboptimal Cholesterol Levels

Federica Fogacci; Marina Giovannini; Antonio Di Micoli; Giulia Fiorini; Elisa Grandi; Claudio Borghi; Arrigo F.G. Cicero

doi:10.3390/nu16111587

May 23, 2024NutrientsOpen Access

A Randomized, Double-Blind, Placebo-Controlled Clinical Trial on the Effect of a Dietary Supplement Containing Dry Artichoke and Bergamot Extracts on Metabolic and Vascular Risk Factors in Individuals with Suboptimal Cholesterol Levels

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Key Points

Supplementation with artichoke and bergamot extracts significantly improved lipid levels, lowering low-density lipoprotein cholesterol and apolipoprotein b-100 compared to placebo.
In this randomized, double-blind, placebo-controlled clinical trial across 12 weeks, active treatment significantly reduced high-sensitivity c-reactive protein and fatty liver index.
These findings highlight that combined polyphenolic supplementation may attenuate cardiovascular risk and markers of non-alcoholic fatty liver disease in patients with dyslipidemia.

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Implication

Randomized double-blind trial reveals reduced lipid concentrations and hepatic markers in individuals with suboptimal cholesterol levels, suggesting therapeutic value for cardiovascular risk.

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Fogacci et al. (2024) studied this question.

synapsesocial.com/papers/68e68ac7b6db643587612f03 https://doi.org/10.3390/nu16111587

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A Randomized, Double-Blind, Placebo-Controlled Clinical Trial on the Effect of a Dietary Supplement Containing Dry Artichoke and Bergamot Extracts on Metabolic and Vascular Risk Factors in Individuals with Suboptimal Cholesterol Levels

Key Points

No abstract yet

Implication

Discussion

Cite This Study

A Randomized, Double-Blind, Placebo-Controlled Clinical Trial on the Effect of a Dietary Supplement Containing Dry Artichoke and Bergamot Extracts on Metabolic and Vascular Risk Factors in Individuals with Suboptimal Cholesterol Levels

Key Points

No abstract yet

Implication

Discussion

Cite This Study

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