Pain treatment individualization in patients with advanced cancer using immediate release morphine

Adequate pain relief through individual tailoring of the basic analgesic in suited dose and drug formulation, as well as the use of adjuvant and supportive therapy, relieves the suffering of patients with advanced cancer in most cases. Noninvasive opioids in immediate and modified release formulations play a key role in treating severe chronic pain syndrome. We present a series of case studies to illustrate morphine tablet and oral solution administration as part of an individual pain therapy regimen, such as opioid dose titration, treatment of breakthrough pain, and around-the-clock pain control.