Human Monkeypox Proctitis

A 30-year-old man was admitted to the hospital with a 4-day fever and a 2-day anorectal pain.He reported having anal intercourse with a new male partner 5 days before the onset of his symptoms.The patient had no recollection of any skin lesions on his partner and was confused about whether the partner had signs of human monkeypox (mpox).Vesicles were observed in his throat, face, trunk, and limbs following a physical examination.Anorectal examination indicated perianal erosion (Figure 1a).Two samples were collected from the face and wrist using the protocol recommended by the World Health Organization. 1 Real-time polymerase chain reaction was performed at the Tokyo Metropolitan Institute of Public Health using the same procedure described in the reference. 2The mpox viral gene was found in both skin lesions.Human immunodeficiency virus, syphilis, Chlamydia trachomatis, Neisseria gonorrhea, and herpes simplex virus 1 and 2 were not detected during sexually transmitted disease screening.