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May 18, 2024World Journal of Surgical OncologyOpen Access

HHLA2 deficiency inhibits pancreatic cancer progression and THP-1 macrophage M2 polarization via EGFR/MAPK/ERK and mTOR/AKT pathway

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Authors

SZSiqi ZhouZWZhangding WangDZDian Zhao

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Zhou et al. (2024) studied this question.

synapsesocial.com/papers/68e6983db6db64358761deafhttps://doi.org/10.1186/s12957-024-03409-2
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1HHLA2 promotes hepatoma cell proliferation, migration, and invasion via SPP1/PI3K/AKT signaling pathway2024 · 14 citations
  2. 2Comparison of mismatch repair and immune checkpoint protein profile with histopathological parameters in pancreatic, periampullary/ampullary, and choledochal adenocarcinomas2024 · 2 citations
  3. 3Clinical Evaluation of HHLA2 in Hormone Receptor-Positive Breast Cancer: Expression Patterns and Prognostic Implications2026
  4. 4Unlocking the potential of HHLA2: identifying functional immune infiltrating cells in the tumor microenvironment and predicting clinical outcomes in laryngeal squamous cell carcinoma2024 · 5 citations
  5. 5Prognostic Value of HHLA2 in Patients with Solid Tumors: A Meta-Analysis2024 · 3 citations