Clinicopathological Features of Plasmacytoid Urothelial Carcinoma of the Bladder: Case Report and Review of the Literature

Plasmacytoid Urothelial Carcinoma (PUC) is a rare histological variant of bladder cancer accounting for 1% to 3% of all urothelial bladder cancer worldwide. This aggressive tumor is associated with poor prognosis and is often metastatic at diagnosis. These characteristics lead to the need of a differential diagnosis where histopathological examination, together with the use of immunohistochemistry are crucial. In this case report we report a 62-year-old female patient affected by urothelial carcinoma with plasmacytoid differentiation.