Exploratory study demonstrates the feasibility of immediate surgery in men with PIRADS 5 lesions, suggesting biopsy omission may reduce treatment delays.
Conventionally, confirmation of clinically significant prostate cancer (csPCa) (Gleason grade group ≥ 2) involves an initial multiparametric magnetic resonance imaging (mpMRI) followed by biopsy. Prostate biopsy incurs inherent risks of infection, bleeding, patient discomfort, and a 6-week delay before robot-assisted laparoscopic radical prostatectomy (RALP). We explored the feasibility of immediate RALP in men with PIRADS 5 lesions without preceding biopsy.
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Razdan et al. (2024) studied this question.
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