Updates from the 2022 WHO Classification of Kidney Epithelial Tumors

During the past few years, numerous advances have been made in the characterization and categorization of renal tumors, particularly malignant tumors. During these years, new treatment approaches have also been developed, along with the emergence of new molecular data on renal tumors, paving the way for precision diagnostics and therapeutics. The World Health Organization (WHO) Classification of Tumors series for urinary and male genital tract tumors represents the major global platform for updates in the pathology of urological cancers including renal cell carcinoma. The latest WHO classification was published in 2022 and incorporates significant changes from the previous (WHO 2016) classification. The aim of this review is to describe the diagnostic updates and the major changes in the latest classification of kidney epithelial tumors and the rationale behind these changes.