Diarylacetylenes undergo anti-dimagnesiation using magnesium bromide and sodium dispersion to afford (E)-1,2-dimagnesioalkenes. This dimagnesiation utilizes simple magnesium bromide as a reduction-resistant electrophile, contrasting with the previously reported dimagnesiation using tricky organomagnesium halides. The resulting vicinal double Grignard reagents react with various electrophiles to yield multisubstituted alkenes stereoselectively.
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Yorimitsu et al. (2024) studied this question.
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