Pharmacotherapies for essential hypertension: an in-depth review

Hypertension, a widespread global health concern a ecting a staggering 1.28 billion adults, poses a signi cant challenge due to its silent nature and inadequate management rates.This article provides an evidence-based approach to common pharmacotherapies for essential hypertension, analyzing their e cacy and safety.We will explore guidelines on target blood pressure goals and discuss rst-line agents such as angiotensin-converting enzyme inhibitors (ACEIs), angiotensin 2 receptor blockers (ARBs), calcium channel blockers (CCBs), thiazide diuretics, and beta-blockers.The review highlights emerging evidence on combination therapies and addresses adverse e ects.The objective of this comprehensive overview is to provide guidance for clinical decision-making and enhance patient outcomes.