Advancements in Drug Monitoring: A GC-MOS Approach for Propofol Measurement

This paper presents a novel application of Gas Chromatography-Metal Oxide Semiconductor (GC-MOS) gas sensor systems for the quantitative measurement of propofol in exhaled air. By integrating advanced MOS sensor technology and analytical techniques, the presented GC-MOS-detector demonstrates quantification abilities similar to the GC-MS system. The results promise great potential for miniaturization and shortening of measuring cycles for drug monitoring in e.g. anesthetic applications with propofol. The proposed setup demonstrates great selectivity in a low-cost solution for propofol measurement.