Syncope secondary to recurrent episodes of torsade de pointes following androgen-deprivation therapy: a case report

Background : Abiraterone has applications in the treatment of prostate cancer.It can potentially be associated with various cardiac arrhythmias, such as torsade de pointes.We report a case where the patient experienced syncope episodes following the administration of this medication, and torsade de pointes was detected during monitoring.Case summary: A 73-year-old man with a history of hypertension and prostate cancer presented to the emergency department with complaints of syncope.He was taking medications for his conditions, including abiraterone acetate and bicalutamide.An ECG revealed a prolonged QT interval and continuous cardiac monitoring showed multiple premature ventricular contractions (PVCs) followed by torsade de pointes.The