Bovine respiratory disease (BRD) is a multifactorial disease complex resulting from interactions among host immunological response, environmental conditions and polymicrobial components. Metaphylaxis, or the mass administration of an antimicrobial upon arrival to a stocker or feedlot facility, is the primary method of control for BRD. Our objective was to determine the influence of 6 different antimicrobials used metaphylactically on the whole blood host transcriptome in healthy steers upon and following arrival to the feedlot.
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Bigelow et al. (2024) studied this question.
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