Relevance. Premenstrual syndrome (PMS) is an urgent gynecological problem. Timely diagnosis and treatment are necessary to ensure a normal quality of life for patients. Aim. To improve the results of treatment of severe pain manifestations and disorders of the antinociceptive system in women with premenstrual syndrome (PMS) based on the identified pathogenetic mechanisms. Materials and methods. 158 women of reproductive age were examined. The women were divided into two groups: the main group consisted of 70 women (with clinical manifestations of PMS) and the control group included 88 women of reproductive age with no complaints and a regular menstrual cycle. Conclusion. The article analyzes modern ideas about the pathogenesis of PMS, and also demonstrates the severity of algic manifestations in women suffering from premenstrual syndrome.
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Ткаченко et al. (2024) studied this question.
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