Comparative short-term outcomes of double-kissing culotte and culotte techniques in acute coronary syndrome: A Multicenter Retrospective Study

Abstract The double-kissing (DK) culotte technique, a modification of the traditional culotte stenting with additional kissing balloon inflation after first stent implantation, was compared to the conventional culotte technique in a multicenter, observational, retrospective study of 239 patients with acute coronary syndrome. Patients were treated at two high-volume centers, with 117 patients undergoing the DK culotte and 122 patients undergoing the traditional culotte technique. The primary endpoint, target lesion failure (TLF), occurred in 6.84% of the DK culotte group and 13.11% of the culotte group after a one-year period (p = 0.085). Major adverse cardiac events (MACE) were also lower in the DK culotte group (12.82% vs. 19.67%; p = 0.073), but the differences were not statistically significant. No significant differences were found in contrast medium use (220 mL vs. 230 mL; p = 0.214) or cumulative radiation dose (1868 mGy vs. 2114.5 mGy; p = 0.127). The results indicate a trend towards better clinical outcomes with the DK culotte technique without increased procedural risks. However, these findings need further validation in prospective studies. ClinicalTrials.gov: NCT06284057